Whats’ the difference of ubiquinol and ubiquinone? Nutra Biotech Co.,Ltd
Ubiquinol, also known as reduced Coenzyme Q10,is the advanced ubiquinone.
There are two forms of coenzyme Q10 in human body.
One is oxidized coenzyme Q10 (ubiquinone)
The other is reduced coenzyme Q10 (Ubiquinol)
– The total content of coenzyme Q10 in the human body is about 1% to 2%.
– Ubiquinol is as high as 98% to 99%, which is the main form of coenzyme Q10 in human tissues.
Ubiquinol is an electron-rich (reduced) form of coenzyme Q10.
The natural ubiquinol form of coenzyme Q10 is 2,3-dimethoxy-5-methyl-6-poly prenyl-1,4-benzoquinol, where the polyprenylated side-chain is 9-10 units long in mammals. Coenzyme Q10 (CoQ10) exists in three redox states, fully oxidized (ubiquinone), partially reduced (semiquinone or ubisemiquinone), and fully reduced (ubiquinol). The redox functions of ubiquinol in cellular energy production and antioxidant protection are based on the ability to exchange two electrons in a redox cycle between ubiquinol (reduced) and the ubiquinone (oxidized) form
Coenzyme Q10 (CoQ10) used in products such as supplements sold to date in the market is basically “oxidized”(ubiquinone).
But in fact, most of the CoQ10 in the body is “reduced”! That is to say, the “oxidized” CoQ10 (ubiquinone) has to emit energy and must be converted (reduced) into a “reduced type” (Ubiquinol) in the body. However, the ability to convert in the body diminishes with age. If you have previously felt that the amount of coenzyme Q10 is not enough, it may be because the coenzyme Q10 you have previously taken is “oxidized”.
The reduced coenzyme Q10 can directly emit energy and directly help the body to generate energy. “Reduced” is a coenzyme Q10 that can be easily experienced.
When energy is produced, a strong “reduced” <—> “oxidized” cyclic reaction occurs continuously. This cyclic reaction is more effective when the reduced coenzyme Q10 is increased.
As the age increases and the pressure increases, the amount of “reduced coenzyme Q10” in the body decreases! And the conversion ability from “oxidation type” to “reduction type” is weakened.
Only the “reduced” Q10 can make you feel its own energy!
It is well-established that CoQ10 is not well absorbed into the body, as has been published in many peer-reviewed scientific journals. Since the ubiquinol form has two additional hydrogens, it results in the conversion of two ketone groups into hydroxyl groups on the active portion of the molecule. This causes an increase in the polarity of the CoQ10 molecule and may be a significant factor behind the observed enhanced bioavailability of ubiquinol.